Frequently Asked Question
Frequently Asked Question
Faq For Nephrology
Kidneys are a pair of bean shaped organs located at the upper and backside of the abdomen just under the ribs. Kidneys are the excretory organs of the body. A large amount of blood passes through the kidney every minute and harmful toxins and waste products produced out of metabolism are filtered and removed by the kidneys in form of urine. Apart from removing wastes, kidneys help in maintaining hemoglobin levels, bone health, blood pressure, and levels of minerals in the body in the right amount.
The commonest causes of kidney diseases are uncontrolled blood pressure and diabetes mellitus. Long-term use of pain killers are another major cause of kidney ailments. Apart from these, hereditary diseases and autoimmune diseases can also affect the kidneys.
Most kidney diseases tend to remain asymptomatic till its too late. Your doctor may suspect kidney involvement based on other conditions that you may be suffering from and order tests. Routinely, kidney diseases are identified by urine tests, ultrasonography of the kidney, and level of creatinine and urea in the blood.
This is a condition where the kidneys are not able to remove the waste products from the body. This may be mild, moderate or severe, where the kidneys fail to function completely.
Usually, one kidney is sufficient to excrete all waste products from the body. When kidneys fail (manifested by elevation in blood values of creatinine and urea) both kidneys are affected. However, there are conditions where only one kidney may be involved, but such conditions usually do not present with kidney failure or elevation in serum creatinine.
Acute kidney injury – This is a condition where in there is sudden deterioration of kidney function which occurs over a short period of time (hours to days) and is usually precipitated by conditions affecting other organs in the body. Kidney failure in Acute kidney injury is often temporary, and usually recover either completely or partially. Chronic Kidney Disease – This condition is characterized by a slow, progressive and irreversible loss of kidney function that takes place over several months to years. This is a non-curable condition and kidney function declines gradually and continuously. After a long period (depending on the condition causing the failure) the kidney function may reduce to a stage where the kidney stops working almost completely. This advanced stage of disease is called end stage kidney disease and may culminate to initiation of dialysis.
Symptoms vary as per the severity of the disease. Often, the disease is asymptomatic during the early phase and there may be no warning symptoms.
Certain hints of the disease may be increased urination at night, high blood pressure, frothing of urine, abnormal urine test and high serum creatinine on routine investigations. Other traditional symptoms of kidney diseases including swelling, loss of appetite, nausea, weakness, breathlessness. The disease may go undetected until the kidneys are severely damaged and patients may present with advanced kidney failure. At this advanced stage the patients are usually symptomatic with complaints such as severe nausea, vomiting, weakness, breathlessness, pallor, confusion and convulsions.
Diabetes and high blood pressure are the commonest cause of chronic kidney disease. The recent CKD registry from India found the following to be other common causes of kidney disease.
Glomerulonephritis
Drugs (eg. Painkillers) causing kidney damage
Recurrent kidney infection
Polycystic kidney disease: An inherited disease which causes cysts in the kidney.
CAPD
CAPD, better understood as continuous ambulatory peritoneal dialysis, is a modality which uses the inner lining of your belly to act as a filter to remove waste products. Also, known as water-based dialysis, peritoneal dialysis involves periodic instillation and removal of a special fluid in and out of your belly.
A soft plastic tube is placed in your abdomen by a small surgery. A special sterile fluid is instilled into your belly through this catheter. After the filtering process is finished, the fluid is removed from your body through the catheter.
There are 2 types of peritoneal dialysis –
CAPD -Continuous ambulatory peritoneal dialysis
APD – Automated Peritoneal Dialysis
The basic mechanism is the same for each. However, the number of treatments, use of a machine, and how the treatment is done differs between the two.
CAPD is done manually, is “continuous,” without the use of a machine and done while performing normal activities such as work or school. The treatment is performed by instilling about two litres of cleansing fluid(dialysate) into your belly and later draining it. This is done by connecting a plastic bag of cleansing fluid to the tube in your belly. The fluid enters your belly under the action of gravity and it drained after a certain amount of time. This process usually is done three, four or five times in a day while you are awake during normal activities. Each exchange takes about 30 to 40 minutes.
APD employs a machine (cycler) that delivers and then drains the cleansing fluid for you. The treatment usually is done at night while you sleep.
This depends the on the characteristics of the inner lining of your belly which is understood by performing special tests. Your personal choice and your condition in borne is mind and your doctor will help you make the choice.
Some doctors believe that CAPD and APD have several benefits when compared to hemodialysis.
In CAPD, continuous dialysis takes place. Peritoneal dialysis is usually a daily process, similar to the working of the kidney and may be gentler with fluid removal from the body. This may reduce stress on the heart and blood vessels. Peritoneal dialysis is an effective form of dialysis, has been proven to be as good as hemodialysis
Also, peritoneal dialysis provides the benefit of performing the treatment at home for shorter periods and enables you to perform more of your daily activities and it is easier to work or travel.
However, peritoneal dialysis may not be appropriate for some patients. These patients include those who are morbidly obese, have had multiple previous surgeries rendering the abdomen unsuitable for dialysis.
Peritonitis (infection of abdomen) is an occasional complication although should be infrequent with appropriate precautions.
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Peritoneal dialysis is not for everyone. People must receive training and be able to perform correctly each of the steps of the treatment. A trained helper may also be used.
- What should be the dietary changes that I must follow once I start peritoneal dialysis?
The dietary suggestions on peritoneal dialysis are different from those followed when patients are not on dialysis. Your dietitian will help you plan your meals to make sure that you get the proper balance. Here are some general guidelines:
Protein:
In patients not on dialysis, protein is usually restricted in diet as the kidneys are not able to remove the waste products of protein metabolism adequately.
Once peritoneal dialysis is initiated, along with the clearing of urea, your body loses proteins that are normally retained in your blood.
This can lead to malnutrition and you will now need to eat more protein to replace what is lost.
It is important to consider the type of protein you eat. Animal sources such as eggs, fish, chicken are rich in high quality protein. Plant sources such as vegetables and grains are poor sources and provide low quality protein. If possible protein intake should be of high quality. Your dietitian can help you decide a meal plan so that you get the right balance.
Calories:
Calories give your body energy. During peritoneal dialysis calories are derived both from the food you eat as well as from the sugar in the dialysate solution. This sugar helps remove fluid from the body, but some of it also gets absorbed in the body and contributes to calorie intake. This can cause unwanted weight gain.
Potassium:
Potassium is an electrolyte which is tightly regulated by the kidneys. Too much or too little concentration in blood can cause serious complications and its level should and will be watched closely. For most patients, foods containing potassium need to be restricted from the diet. It is plentiful in dried fruits, dried beans and peas, nuts, meat, milk, fruits and vegetables and also in salt substitutes.
Hemodialysis
Dialysis is a process of artificially removing excess water, toxins, solutes from the blood of the people using a machine, in patients whose kidneys are unable to perform these functions naturally.
When kidneys cannot remove enough wastes and excess water from the body, it may be necessary to initiate dialysis. This usually happens when you only 10 to 15 percent of kidney function is left. There is no defined cut-off value of creatinine when dialysis should be initiated. Based on your symptoms such as difficulty in breathing, poor appetite, recurrent vomiting, your doctor will decide if dialysis is needed.
Hemodialysis is performed using a machine which enables the blood to pass through an artificial filter (dialyzer). Waste products are cleared by the filter and the “clean” blood is then returned to the body. In order to ensure adequate amount of blood gets cleared, it is necessary to create an access or entry into your blood vessels. This access is called a ‘fistula’, which is a minor surgery in your arm / forearm.
During dialysis the blood passes through the dialyzer. The dialyzer, or filter, has two compartments, one for your blood and one for a washing fluid called dialysate. A thin membrane separates these two parts. This membrane prevents removal of important constituents of blood such as blood cells, protein etc and only removes smaller waste molecules namely creatinine, urea.
There are multiple options. Dialysis can be performed in hospital, in a dialysis centre and even at home. However, this needs to be decided after considering the patients condition and needs and requires a joint decision by you and your doctor.
Hemodialysis is commonly done 3 times a week with each session of 4 hours on average. Those who choose to do dialysis at home, may get dialysis done more frequently, with shorter sessions each time.
Your dialysis prescription needs to be decided by doctor after taking into consideration your symptoms, reports and the amount of urine passed per day. Studies have shown that getting the right amount of dialysis improves your overall health, keeps you out of the hospital and enables you to live longer.
It is possible to do dialysis at home, but this needs to be decided on case-by-case basis.
Patients with kidney disease who are not on dialysis are usually on lot of dietary restrictions. This changes once the patient starts dialysis. The patients are then advised to increase their protein intake and limit the amount of potassium, phosphorus, sodium, and fluid in their diet. Additional dietary changes may be applicable to patients with diabetes or other health conditions. It’s important to talk with you dietitian about your individual diet needs.
Dialysis is a modality which substitutes kidney function in times of failure. It removes toxins which are otherwise removed by the kidneys. Dialysis thus clears off toxic waste from the body which can otherwise become life-threatening. However, dialysis in itself, alone, cannot cure your underlying condition.
In cases of sudden or acute kidney failure, dialysis may be needed for a short time until the kidneys start working better. However, when kidney disease progresses to kidney failure over a longer period of time, your kidneys do not get better and you will need dialysis for the rest of your life unless you receive a kidney transplant.
The common discomforts faced by patients on dialysis are –
Needle pricks – needles inserted in fistula or graft at every dialysis. However, most patients get used to this over few days. Local anesthetic creams may be used prior to needle insertion which may reduce the discomfort. Your dialysis team will make you as comfortable as possible.
Symptoms like cramps, headaches, nausea or dizziness can occur and these often be managed easily.
Some of the steps that could help you include:
- Slowing down your fluid removal, but this could increase your dialysis time / frequency.
- Increasing the amount of sodium in your dialysate.
- Adjusting your dry weight, or target weight.
- Cooling the dialysate a little.
Many symptoms can be mitigated by following your diet and fluid allowances. The need to remove too much fluid during dialysis is one of common things that causes problems and discomfort during dialysis.
Dialysis treatment can be expensive. However, the Indian government’s Ayushman program, Rajiv Gandhi Yojana and other schemes help cover costs of dialysis for many patients. Several charitable centres and NGOs help provide dialysis at reasonable rates. Corporate centres and hospitals exist too, however the dialysis rates even at these centres (in Mumbai) are one of the cheapest in the country. Private health insurance or state medical aid may also help with the costs.
Yes. Dialysis centres are located in every part of India and many foreign countries. You can access the dialysis directory which lists all the dialysis centres in the country on the website – www.mumbaikidneyfoundation.in
Yes. Many patients continue to or return to active work once they are on regular dialysis.
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